Alternatives
Other ways to take a GLP-1 medicine
Rybelsus was the first GLP-1 tablet. It now has company: a higher-dose semaglutide pill for weight loss, a new pill from Lilly with no fasting rule, and cheaper generic injections in some countries.
Tablets
Tablet · once dailyWegovy pillsemaglutide (oral) · Novo NordiskWeight management, cardiovascular risk reductionTablet · once dailyFoundayoorforglipron · Eli LillyWeight management, type 2 diabetes
Injections
Injection · once weeklyOzempicsemaglutide (injection) · Novo NordiskType 2 diabetes, cardiovascular risk reductionInjection · once weeklyWegovysemaglutide (injection) · Novo NordiskWeight management, cardiovascular risk reductionInjection · once weeklyMounjarotirzepatide · Eli LillyType 2 diabetes, weight management, cardiovascular risk reductionInjection · once weekly (injections); once daily (oral tablets in India)Generic semaglutidesemaglutide · Various (e.g. Dr. Reddy's, Apotex, Sandoz, Sun Pharma, Zydus, Torrent, EMS)Type 2 diabetes, weight management
Head-to-head comparisons
Rybelsus comparedRybelsus vs OzempicSame molecule, different route: how the daily semaglutide tablet compares with the weekly Ozempic injection. Rybelsus comparedRybelsus vs Wegovy pillTwo semaglutide tablets, one for type 2 diabetes and one for weight management: doses, trials and availability compared. Rybelsus comparedRybelsus vs FoundayoOral semaglutide vs orforglipron: routine, licences, the ACHIEVE-3 head-to-head trial and side effects compared. Rybelsus comparedRybelsus vs MounjaroDaily semaglutide tablet vs weekly tirzepatide injection: how they work, licences, trial results and side effects. Rybelsus comparedRybelsus vs WegovyA daily diabetes tablet and a weekly weight-management injection, both semaglutide: licences, doses and trials compared. Rybelsus comparedRybelsus vs metforminFirst-line metformin vs the Rybelsus GLP-1 tablet: guidelines, results, side effects and the 30-minute rule for taking both. Rybelsus comparedRybelsus vs JardianceSemaglutide tablet vs empagliflozin and dapagliflozin: PIONEER 2, heart and kidney outcomes, side effects and combination use. Rybelsus comparedRybelsus vs JanuviaSemaglutide tablet vs sitagliptin: how each works on GLP-1, PIONEER 3 results, side effects, weight and why they are not combined.
Where each one is available
Hover or tap a status for details. Country pages have the full picture.
| Country | Rybelsustablet | Wegovy pilltablet | Foundayotablet | Ozempicinjection | Wegovyinjection | Mounjaroinjection | Generic semaglutideinjection |
|---|---|---|---|---|---|---|---|
| US United States | Availableas Ozempic pill | Available | Available | Available | Available | Available | Not approved |
| UK United Kingdom | Available | Availableas Wegovy tablets (Wegovy pill) | Available | Available | Available | Available | Not approved |
| CA Canada | Available | Unconfirmed | Under review | Available | Available | Available | Availableas Semaglutide Injection (Dr. Reddy's), Apo-Semaglutide and Sevmia (Apotex) |
| AU Australia | Approved, not launched | Not approved | Under review | Available | Available | Available | Not approved |
| IE Ireland | Approved, not launched | Approved, not launchedas Wegovy tablets | Under review | Available | Available | Available | Under review |
| NZ New Zealand | Unconfirmed | Unconfirmed | Unconfirmed | Unconfirmed | Available | Available | Unconfirmed |
| DE Germany | Approved, not launched | Availableas Wegovy tablets | Under review | Available | Available | Available | Under review |
| FR France | Approved, not launched | Approved, not launchedas Wegovy tablets | Under review | Available | Available | Available | Under review |
| ES Spain | Available | Approved, not launchedas Wegovy 25 mg comprimidos | Under review | Available | Available | Available | Under review |
| IT Italy | Available | Approved, not launchedas Wegovy tablets | Under review | Available | Available | Available | Under review |
| NL Netherlands | Available | Approved, not launchedas Wegovy tablets | Under review | Available | Available | Available | Under review |
| AE United Arab Emirates | Available | Availableas Wegovy | Available | Available | Available | Available | Unconfirmed |
| IN India | Available | Unconfirmed | Under review | Available | Available | Available | Availableas Obeda, Semalix, Sembolic (tablets); many injectable brands |
| SG Singapore | Available | Unconfirmed | Unconfirmed | Approved, not launched | Approved, not launched | Approved, not launched | Unconfirmed |
| ZA South Africa | Approved, not launched | Not approved | Not approved | Available | Available | Available | Approved, not launchedas Semagard |